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iCAPs_v2/main_Clustering.m
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main_Clustering.m
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%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
% DESCRIPTION
% This is supposed to be the main script used to run total activation and
% clustering of total activation outputs into innovation-driven
% co-activation patterns
%
% REFERENCES
% For theoretical references about those techniques and applications to
% functional brain imaging, see the following:
%
% - A Signal Processing Approach to Generalized 1-D Total Variation
% (Karahanoglu et al., IEEE Transactions on Signal Processing, vol. 59, no.
% 11, November 2011) for details on the linear operator used in total
% activation (deconvolution coupled to derivation) and its discrete
% implementation
%
% - Total activation: fMRI deconvolution through spatio-temporal
% regularization (Karahanoglu et al., Neuroimage, vol. 73, pp. 121-134,
% 2013) for an overview of total activation in its first version (still
% used as such for temporal regularization; see Appendix A. for an outline
% of the algorithm)
%
% - Transient brain activity disentangles fMRI resting-state dynamics in
% terms of spatially and temporally overlapping networks (Karahanoglu et
% al., Nature communications, DOI: 10.1038/ncomms8751, 2015) for an
% application of total activation to resting-state brain data, and the
% introduction of the thresholding and iCAP steps
%
% - Regularized spatiotemporal deconvolution of fMRI data using gray-matter
% constrained total variation (Farouj et al., ISBI abstract, 2016) for an
% overview of the presently used version of spatial regularization
%
%
% ACKNOWLEDGMENTS
% The present codes are adaptations from the initial version developed
% by Dr Isik Karahanoglu, former PhD student at MIP:Lab, and Dr Younes
% Farouj, former visiting PhD student and now post-doc at MIP:Lab
%
% UPDATES ON UTILITIES
% V1.0, December 9th 2016, Thomas Bolton: simplified total activation
% scripts running for one subject (not yet functional)
% V1.1, December 23rd 2016, Thomas Bolton: finished modifying total
% activation routines for one subject
% V1.2, December 28th 2016, Thomas Bolton: everything written down as
% functions for total activation, and tested on .img/.hdr functional and
% segmentation files
% V2.0, May 2018, Daniela Zoeller: including of updates of all lab members:
% - changed structure of results saving
% - separated TA, thesholding, clustering and regression in different
% functions
% - included checking whether TA has already been done
%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%%
clc;clear all;close all;
% Adds the paths required for total activation
AddPaths();
% setting up all parameters to run Clustering
Inputs_Clustering_Data_OpenfMRI
Inputs_Clustering
% run Clustering
Run_Clustering(param);
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