Diffusion PySONIC (old) (master) History

R4670/PySONIC
master0453d1e710dd1ff2a743d83…

May 23 2019

added interface around titrate function to use memory caching
0453d1e710dd
·Theo Lemaire on May 23 2019, 21:01.
added "PI" type control of convergence in nbls.evaluateStability method
678bec02c372
·Theo Lemaire on May 23 2019, 19:03.

May 22 2019

implemented neuron-dependent titration to find specific thresholds (excitation…
1a5f9b3c215b
·Theo Lemaire on May 22 2019, 19:07.
added max integration duration to stability analysis to avoid infinite loops in…
0ee058e8778d
·Theo Lemaire on May 22 2019, 15:48.
implemented quasiSteadyStateFixedPoints as part of nbls class. Added…
3addfe632329
·Theo Lemaire on May 22 2019, 11:42.
implemented nbls.quasiSteadStateiNet method, used to compute Q-SFPs iteratively…
2024b001441b
·Theo Lemaire on May 22 2019, 09:36.

May 21 2019

added nA command line argument to plot_QSS_IQ.py
6b55fdb84a7a
·Theo Lemaire on May 21 2019, 19:08.
implemented specific nbls evaluateStability method to evaluate FP stability by…
8a17ab2f8c11
·Theo Lemaire on May 21 2019, 18:06.

May 20 2019

added negative offset to QSS perturbation
14f3b43f5ec7
·Theo Lemaire on May 20 2019, 18:02.

May 17 2019

added warning note about why QSS cannot be interpolated accurately and must be…
df4bf6f7892b
·Theo Lemaire on May 17 2019, 19:35.
added fixed point classification based on perturbation reaction in QSS analysis.
3e55319aff15
·Theo Lemaire on May 17 2019, 19:26.
added isTitratable method to neuron classes. improved QSS SFP stability…
4d8fa0caef5b
·Theo Lemaire on May 17 2019, 16:22.

May 16 2019

replaced linear interpolation of QSS at Q-SFPs (inaccurate) by full…
3ad8ad914eec
·Theo Lemaire on May 16 2019, 17:18.
added np.nan bounding to all np.interp uses in the code. implemented…
3f4135902bdc
·Theo Lemaire on May 16 2019, 15:30.

May 15 2019

implemented getLookupsDCavg function to compute DC-averaged lookups. nbls.
a66b375c6133
·Theo Lemaire on May 15 2019, 16:36.
simplified nbls.quasiSteadyStates method, now calling explicit quasiSeadyStates…
ee9cf8652b7e
·Theo Lemaire on May 15 2019, 13:53.

May 14 2019

changed PointNeuron getEffrates, steadyStates, derStates and derEffStates…
62c6723c6e71
·Theo Lemaire on May 14 2019, 19:21.

May 10 2019

major improvements to QSS module
7a27b761d220
·Theo Lemaire on May 10 2019, 18:09.

May 6 2019

added ref mode to QSSvar with phase plot arrows.
536de29806e2
·Theo Lemaire on May 6 2019, 19:15.

Apr 29 2019

corrected titrate function to work also with negative injected currents (for…
44780023da34
·Theo Lemaire on Apr 29 2019, 12:09.

Apr 8 2019

adapted plotQSSVarVsAmp and plotEqChargeVsAmp functions for ESTIM use (not…
ddab2a4571ea
·Theo Lemaire on Apr 8 2019, 23:07.

Apr 5 2019

added Qi-conditional graphs labeling for plotQSSVarVsAmp and plotEqChargeVsAmp
f7c982e3c3ea
·Theo Lemaire on Apr 5 2019, 21:12.
corrected nbls.quasiSteadyStates to return DC-averaged Vmeff, and adapted nbls.
490706425b05
·Theo Lemaire on Apr 5 2019, 21:04.
improved titrate function with nSpikes methods pneuron and nbls classes. added…
6ffd825273a4
·Theo Lemaire on Apr 5 2019, 17:47.

Apr 4 2019

Changed titration functions (now using generic titrate), Implemented Xinf…
9f09f2fdc039
·Theo Lemaire on Apr 4 2019, 13:38.

Mar 26 2019

added generic plot_QSS_IQ.py script to plot the IQ phase-plane diagram for a…
178930fa846c
·tlemaire on Mar 26 2019, 23:29.
implemented new QSS plot module with generic plotVarDynamics, plotVarsQSS and…
a2726a130bec
·tlemaire on Mar 26 2019, 19:35.
corrected the nbls.quasiSteadyStates method to compute QSS values of slow…
b6c44fad8f0a
·tlemaire on Mar 26 2019, 14:53.
replaced lookups list by lookups dict in all derStatesEff methods. added get…
8a71066a647c
·tlemaire on Mar 26 2019, 11:52.

Mar 20 2019

corrected computation of Cai_ss for STN neuron, now using voltage-gated steady…
5a5f2babbc5d
·tlemaire on Mar 20 2019, 17:12.
corrected nbls.getQSSvars method, now computing non-rate-defined QSS values…
256a4aab9b65
·tlemaire on Mar 20 2019, 15:01.
corrected STN lookups, comparison of temporal profiles of spontaneous activity…
6f96c02c5ecb
·tlemaire on Mar 20 2019, 11:41.

Mar 18 2019

Implemented NmodlGenerator core class to automatically generate NEURON MOD file…
07d55c08e109
·tlemaire on Mar 18 2019, 21:21.
moved membrane currents in 2rd position of neurons pltscheme. extractPltVar now…
cf921135e3f2
·tlemaire on Mar 18 2019, 17:56.

Mar 15 2019

cleaned up neurons docstring. added getDesc method to PointNeurons class.
8623752f128f
·tlemaire on Mar 15 2019, 02:20.
removed old pltvars dictionary.
895dbbeb52ae
·tlemaire on Mar 15 2019, 01:32.
added rates to pneuron.getPltVars method. adapted use in plotEffectiveVariables…
6bc050dea626
·tlemaire on Mar 15 2019, 01:30.
adapted plotComp to new plot variables scheme.
ad0a33b92c3c
·tlemaire on Mar 15 2019, 01:15.
created plt.pltutils module and moved relevant plotting functions into it.
a812d7d527af
·tlemaire on Mar 15 2019, 00:20.

Mar 14 2019

removed states0 attribute from neuron classes (now calling steadyStates method…
81554e5d4d67
·tlemaire on Mar 14 2019, 23:52.
generalized the use of getPltVars and getPltScheme with inheritance scheme…
453f896987ce
·tlemaire on Mar 14 2019, 23:35.
major reformatting of plotBatch function
9d1a2fc5cd08
·tlemaire on Mar 14 2019, 19:09.
cleaned up neurons docstring. defined PointNeuron.getPltVars method (possibly…
f6195a153a01
·tlemaire on Mar 14 2019, 13:38.

Mar 13 2019

major reformatting of neuron classes.
d744944eba53
·tlemaire on Mar 13 2019, 18:35.
implemented PointNeuron.currentToConcentrationRate method for a common way to…
db85dec73950
·tlemaire on Mar 13 2019, 16:08.
replaced CCa_out by Cao and KCa by 1 / taur_Cai in STN class for more clarity.
b178c1dca3c9
·tlemaire on Mar 13 2019, 15:51.
added Qbounds as a PointNeuron class method. cleaned up use of Cai in TC class.
ce5a9df84ba1
·tlemaire on Mar 13 2019, 15:44.
removed all combined gating variables from pltvars schemes.
33c52c6b04a5
·tlemaire on Mar 13 2019, 15:14.
implemented PointNeuron.getCurrentPltVars method to genrate a dictionary plot…
817387c89edd
·tlemaire on Mar 13 2019, 15:00.
replaced iNet method by currents method in all neuron classes (iNet now defined…
09ec0decb4bd
·tlemaire on Mar 13 2019, 10:17.

Mar 12 2019

corrected error in STN.derD1. lookup tables to re-run.
2b5b9cf5a78b
·tlemaire on Mar 12 2019, 12:51.
added get_dCCa and findCaeq methods ot STN neuron (iterative search to find…
7082d86bf3da
·tlemaire on Mar 12 2019, 01:29.

Mar 11 2019

implemented NeuronalBilayerSonophore.getQSSvars method to compute QSS…
d99d9eb144b6
·tlemaire on Mar 11 2019, 20:39.
adapted plotSpikingMetrics for uniform y-axis scale. adapted ASTIM_filecode…
cd145e4db3e8
·tlemaire on Mar 11 2019, 13:55.

Mar 10 2019

added currents methods to Cortical, Thalamic and STN classes, that returns a…
c5433b2c448c
·tlemaire on Mar 10 2019, 19:36.

Mar 8 2019

adapted fig9.py with corrected STN model (new traces).
a74f9c571b7d
·tlemaire on Mar 8 2019, 16:52.
corrected STN lookups. added testQSS script to analyze STN neuron plateau…
e73ca2da1333
·tlemaire on Mar 8 2019, 15:38.

Mar 7 2019

corrected sigmaT2_b from -10 mV to 10 mV in STN implementation. started new QSS…
990c8181cf46
·tlemaire on Mar 7 2019, 16:00.

Mar 6 2019

renamed currents for more clarity
da8e0bbde997
·tlemaire on Mar 6 2019, 17:56.

Mar 5 2019

changed nomenclature of current methods from "curr..." to "i..."
2e64aa90c325
·tlemaire on Mar 5 2019, 12:18.
implemented getLookupsOff function to retrieve US-OFF lookups. adapted…
c72b7b319ed0
·tlemaire on Mar 5 2019, 11:04.

Feb 28 2019

added RS neuron lookups with partial coverage (spatially averaged). updated…
865020d8c630
·tlemaire on Feb 28 2019, 11:41.

Jan 23 2019

corrected error in getLookups2Dfs
702446ca2ad5
·tlemaire on Jan 23 2019, 19:05.
added getLookups2Dfs method to interpolate lookups at given membrane coverage.
957db9d021d6
·tlemaire on Jan 23 2019, 18:15.
added script to compute quick lookups for a span of partial sonophore coverage…
80aa94a42257
·tlemaire on Jan 23 2019, 16:00.

Jan 11 2019

modified Qbounds to account for capacitance value in all neuron types.
69f20e7c2a18
·tlemaire on Jan 11 2019, 08:50.
added lookups for FH membrane mechanism (tested)
cf20bd8f6516
·tlemaire on Jan 11 2019, 08:26.

Jan 10 2019

corrected Qbounds for lookups generation in FH neuron
8684707c3f08
·tlemaire on Jan 10 2019, 12:31.

Jan 9 2019

changed PMAVG_STD_ERR_MAX value to allow BLS lookups generation for FH…
82590fe13581
·tlemaire on Jan 9 2019, 18:05.
implemented Frankenhaeuser-Huxley membrane mechanism (validated against data…
65c1d8649331
·tlemaire on Jan 9 2019, 17:59.

Dec 27 2018

corrected error in Vm post-processing in runSONIC. added plotV option to…
8a4719662fd9
·tlemaire on Dec 27 2018, 19:08.

Dec 14 2018

modified plotActivationMap to plot amplitude thresholds computed from titration…
42f56ab271e3
·tlemaire on Dec 14 2018, 18:16.

Dec 9 2018

added pltvars for STN neuron. added plotFRprofile function along with paper…
0fcd53a68ce7
·tlemaire on Dec 9 2018, 16:17.

Dec 4 2018

added STN lookups and corrected derEffStates method.
e99b70b6952c
·tlemaire on Dec 4 2018, 01:20.

Dec 3 2018

corrected STN getEffRates and derStatesEff methods for correct lookups creation…
7655cca494a0
·tlemaire on Dec 3 2018, 21:52.
STN model validated for E-STIM by reproduction of key features (spontaneous…
9eca746695d1
·tlemaire on Dec 3 2018, 17:46.

Nov 30 2018

replaced 'L' by 'Leak' in neurons nomenclature. implemented STN neuron with…
0ebd7ae3b932
·tlemaire on Nov 30 2018, 10:37.

Nov 29 2018

added plotFRspectrum function to actmap module. updated fig7 script, and added…
850b05b61c5e
·tlemaire on Nov 29 2018, 16:00.

Nov 27 2018

added spanDC argument to run_astim. removed rheobase amp preconditioning in…
fa4c643a5a4b
·tlemaire on Nov 27 2018, 16:18.
recomputed lookups for all CNS neurons. modified figs 5 and 6 generation…
84a00ea7e59b
·tlemaire on Nov 27 2018, 11:28.

Nov 25 2018

added recording of computation times during lookups creation.
9f827c942524
·tlemaire on Nov 25 2018, 01:10.

Nov 22 2018

improved plotRheobaseAmps function. improved arguments parsing in command line…
2f63e4926c36
·tlemaire on Nov 22 2018, 17:58.

Nov 20 2018

modified getLookups2D to project along any dimensions pair in (a, f, A).
8573c726b480
·tlemaire on Nov 20 2018, 19:32.

Nov 19 2018

modified runSONIC method to use odeint solver with interpolated lookups for…
da009206a90e
·tlemaire on Nov 19 2018, 21:46.

Oct 28 2018

improved plotPhasePlane function. implemented isWithin function for loose bound…
d17615ffb4e6
·tlemaire on Oct 28 2018, 22:49.

Oct 25 2018

plotPhaseDiagram method validated on CW stimuli
35b8bf12ec49
·tlemaire on Oct 25 2018, 22:49.
implemented figtitle method for direct labeling from metadata. implemented…
d2b627754312
·tlemaire on Oct 25 2018, 14:52.

Oct 2 2018

added scripts to generate paper figures automatically.
ed0d192b377b
·tlemaire on Oct 2 2018, 02:55.

Sep 28 2018

updated package documentation
73851d6ac128
·tlemaire on Sep 28 2018, 14:23.
new lookup tables for IB, LeechT and LeechP neurons.
d2bb8612b26e
·tlemaire on Sep 28 2018, 01:13.

Sep 27 2018

revmoved old TC.mod file
3ba84a26398c
·tlemaire on Sep 27 2018, 11:25.
added LTS and TC lookups. corrected errors in run_astim and run_estim arguments…
81ffd1c605f6
·tlemaire on Sep 27 2018, 11:16.
attempt to fix multiprocessing lookups creation.
f5f327799ad4
·tlemaire on Sep 27 2018, 03:03.

Sep 26 2018

removed pltutils file
7075d3ab7f91
·tlemaire on Sep 26 2018, 17:26.
added actmap to plt module, with command line script.
4a67049acd76
·tlemaire on Sep 26 2018, 17:06.
corrected error on lookups dict save.
7bd042cd39f7
·tlemaire on Sep 26 2018, 09:33.

Sep 25 2018

fixed call to plotBatch in run scripts
0412541be120
·tlemaire on Sep 25 2018, 18:03.
moved plotComp and plotBatch functions to separate files. created unique plot…
a35c13583071
·tlemaire on Sep 25 2018, 17:25.
cleaned up deprecated folder. added notebook about balance quasi-steady…
8819bbb0e66f
·tlemaire on Sep 25 2018, 16:13.
cleaned up utils module. removed log templates (now generated on the fly with…
610dc8472dcf
·tlemaire on Sep 25 2018, 14:46.

R4670/PySONICmaster0453d1e710dd1ff2a743d83…

May 23 2019

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R4670/PySONIC
master0453d1e710dd1ff2a743d83…